Trauma
Bickell WH et al.
‘Immediate versus Delayed Fluid Resuscitation for Hypotensive Patients with Penetrating Torso Injuries’.
The New England Journal of Medicine 331, no. 17 (27 October 1994): 1105–1109. doi:10.1056/NEJM199410273311701.The Bottom Line review
CRASH – Roberts I et al.
‘Effect of Intravenous Corticosteroids on Death within 14 Days in 10008 Adults with Clinically Significant Head Injury (MRC CRASH Trial): Randomised Placebo-Controlled Trial’.
Lancet 364, no. 9442 (9 October 2004): 1321–1328. doi:10.1016/S0140-6736(04)17188-2. Wessex ICS Bottom line review
CRASH-2 Shakur H et al.
‘Effects of Tranexamic Acid on Death, Vascular Occlusive Events, and Blood Transfusion in Trauma Patients with Significant Haemorrhage (CRASH-2): A Randomised, Placebo-Controlled Trial’.
Lancet 376, no. 9734 (3 July 2010): 23–32. doi:10.1016/S0140-6736(10)60835-5.
HIPOLYTE – Roquilly A et al.
‘Hydrocortisone Therapy for Patients with Multiple Trauma: The Randomized Controlled HYPOLYTE Study’.
MATTERS – Morrison J et al.
‘Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study’.
PROPPR – Holcomb JB Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial.JAMA. 2015 Feb 3;313(5):471-82. doi: 10.1001/jama.2015.12 Bottom Line review
Burns
Greenhalgh DG et al.
‘American Burn Association Consensus Conference to Define Sepsis and Infection in Burns’.
