2019 Articles

  1. The Association between Supraphysiologic Arterial Oxygen Levels and Mortality in Critically Ill Patients (AmJRCC Dec 2019)
  2. The Effect of Rocuronium vs Succinylcholine on Endotracheal Intubation: Success Rate Among Patients Undergoing Out-of-Hospital Rapid Sequence Intubation  CURASMUR (JAMA Dec 2019) BottomLine review
  3. Prevention of Early Ventilator-Associated Pneumonia after Cardiac Arrest. ANTHARTIC (NEJM Nov 2019) BottomLine review
  4. Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure. CITRIS-ALI (JAMA Oct 2019) BottomLine review
  5. Conservative Oxygen Therapy during Mechanical Ventilation in the ICU. ICU-ROX (NEJM Oct 2019)
  6. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial (Lancet Oct 2019)
  7. Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm. HYPERION (NEJM Oct 2019) – BottomLine review
  8. Effect of a fluid bolus on cardiovascular collapse among critically ill adults undergoing tracheal intubation (PrePARE): a randomised controlled trial. (Lancet Resp Oct 2019)
  9. Pharmacological interventions for the treatment of delirium in critically ill adults (Cochrane review Sep 2019)
  10. Beta-adrenergic blockade for attenuation of catecholamine surge after traumatic brain injury: a randomized pilot trial (BMJ Aug 2019)
  11. Effect of Recombinant Activated Coagulation Factor VII on Hemorrhage Expansion Among Patients With Spot Sign–Positive Acute Intracerebral HemorrhageThe SPOTLIGHT and STOP-IT Randomized Clinical Trials (JAMA neuro Aug 2019)
  12. Diagnosis of elevated intracranial pressure in critically ill adults: systematic review and meta-analysis. (BMJ July 2019)
  13. Effect of an ICU Diary on Posttraumatic Stress Disorder Symptoms Among Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial. (JAMA July 2019) – BottomLine review
  14. Diuretic treatment in high-risk acute decompensation of advanced chronic heart failure – bolus intermittent vs continuous infusion of furosemide. DRAIN.  (June 2019) – BottomLine review
  15. Buffered solutions versus 0.9% saline for resuscitation in critically ill adults and children (Cochrane review July 2019)
  16. Changes in critically ill cancer patients’ short-term outcome over the last decades: results of systematic review with meta-analysis on individual data (June 2019)
  17. Maximal Recruitment Open Lung Ventilation in Acute Respiratory Distress Syndrome (PHARLAP): A Phase II, Multicenter, Randomized, Controlled Trial.(June 2019)
  18. (PEEP) with Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients. PROBESE. (June 2019) – BottomLine review
  19. Impact of furosemide on mortality and the requirement for renal replacement therapy in acute kidney injury: a systematic review and meta-analysis of randomised trials (July 2019)
  20. Early Sedation with Dexmedetomidine in Critically Ill Patients (SPICE III) (June 2019) – BottomLine review
  21. Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome (ROSE) (May 2019) – BottomLine review
  22. Early TIPS with covered stents versus standard treatment for acute variceal bleeding in patients with advanced cirrhosis . AVB-TIPS (May 2019) – BottomLine review
  23. Non-invasive ventilation versus high-flow nasal cannula oxygen therapy with apnoeic oxygenation for preoxygenation before intubation of patients with acute hypoxaemic respiratory failure: a randomised, multicentre, open-label trial (Apr 2019).
  24. Early Manipulation of Arterial Blood Pressure in Acute Ischemic Stroke (MAPAS): Results of a Randomized Controlled Trial (MAPAS) (Apr 2019) – BottomLine review
  25. Balanced Crystalloids versus Saline in Critically Ill Adults (SMART) (Mar 2019) – BottomLine review
  26. Balanced Crystalloids versus Saline in Noncritically Ill Adults (SALT-ED) (Mar 2019)
  27. Early goal-directed haemodynamic optimization of cerebral oxygenation in comatose survivors after cardiac arrest: the Neuroprotect post-cardiac arrest trial (Mar 2019).
  28. Coronary Angiography after Cardiac Arrest without ST-Segment Elevation (Mar 2019)
  29. Non-invasive ventilation versus high-flow nasal cannula oxygen therapy with apnoeic oxygenation for preoxygenation before intubation of patients with acute hypoxaemic respiratory failure: a randomised, multicentre, open-label trial (Mar 2019)
  30. Bag-Mask Ventilation during Tracheal Intubation of Critically Ill Adults (PREVENT) (Feb 2019) – BottomLine review
  31. Adjunctive intermittent pneumatic compression for venous thromboprophylaxis (PREVENT) (Feb 2019) and Nutshell
  32. Early Use of Norepinephrine in Septic Shock Resuscitation (CENSER) : A Randomized Trial.
  33. Effect of Titrating Positive End-Expiratory Pressure (PEEP) With an Esophageal Pressure–Guided Strategy vs an Empirical High PEEP-Fio2 Strategy on Death and Days Free From Mechanical Ventilation Among Patients With Acute Respiratory Distress Syndrome (Feb 2019)
  34. Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock (ANDROMEDA-SHOCK) (Jan2019) TBL review
  35. Effect of a Nurse-Led Preventive Psychological Intervention on Symptoms of Posttraumatic Stress Disorder Among Critically Ill Patients: A Randomized Clinical Trial. (Jan 2019)
  36. Prolonged targeted temperature management reduces memory retrieval deficits six monthspost-cardiac arrest: A randomised controlled trial.(EVALD) (Jan2019) – BottomLine review
  37. Adjunctive Intermittent Pneumatic Compression for Venous Thromboprophylaxis (Jan 2019) TBL review
  38. Comparison of the accuracy of neutrophil CD64, procalcitonin, and C-reactive protein for sepsis identification: a systematic review and meta-analysis (Jan 2019)