Guidelines
NICE guidelines
Studies
Diagnosis
METPSDS – microRNA analysis
VAC – Periitoneal cytokines in open abdomens
NOBIS – novel biomarkers
MitoSepsis – mitochondrial function
Prognosis
PliNOSa – iNOS
ADMA and DDAH II
DYNAMICS:DNA – naked DNA
BNP
Lactate
Copeptin
Therapeutics
Sepsis molecules
OASIS – talactoferrin
AB103
ALP
C1-esterase inhibitor
Proglitazone
Sirtuin-1 activator
CytoFab, anti-TNFalpha
Others
DESIRE – dexmedetomidine
Paracetamol
SEREAL – selenium
SISPCT – selenite and PCT guided antimicrobial therapy
Citrulline
Statins
SAILS – statins for ARDS
Steroids
HYPRESS
ADRENAL
Angiotensin in AKI – ASK-IT
Noradrenaline sparing – ATHOS
Heparin in septic shock – HALO
EGDT
ProCESS
ARISE
AGONIST
ProMISe
Fluids
RASP – Ringers v albumin
Pressors and inotropes
Vasopressin v Noradrenaline – VANCS II
Hypertonic saline and terlipressin – HYSATESS-p
DORESEP – renal function and MAP control
Equipment
BIOVISION – impedance
PiCCO-guidance – THEMIS
Renal
Cascade haemofiltration
HICORES – High dose CVVHF
SAFBT – selective toxin removal
Haematology
ABLE – age of transfused blood in critical illness
TBI
EPO-TBI – erythropoietin and neurological outcome after TBI
Therapeutic hypothermia
CASS – mild hypothermia
EUROTHERM 3235 – in traumatic brain injury
ECMO
ECMO for refractory septic shock
ICU outcomes
ICON – ICU outcomes – ongoing study since 2006
Delirium
HOPE – haloperidol in ICU