Individual topics
Key papers
Cardiovascular and monitoring key papers
Cardiac arrest temperature management angiography medications (inotropes/thrombolysis/antiarrhythmics) ventilation strategy airway pneumonia prevention goal-directed management (eg oxygenation) Septic shock fluids pressors/inotropes steroids metabolic resus / vitamins goal-directed therapy monitoring Fluids Goal-directed therapy Myocardial infarct Heart failure Monitoring
Gastrointestinal and nutrition key papers
Liver Failure (Paracetamol, TIPSS, Hepatorenal Syndrome, Ascites) Pancreatitis Nutrition Route Constituents Timing Residual Volume Ulcer Prophylaxis GI Haemorrhage Probiotics
Governance and ethics key papers
Ethics Human Factors, Error and Teamwork Governance, Quality & Safety etc
Hit parade 2013
Intracranial haemorrhage INTERACT2 – Anderson CS, et al.‘Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage’. New England Journal of Medicine 368, no. 25 (20 June 2013): 2355–2365. doi:10.1056/NEJMoa1214609. Hypovolaemic shock CRISTAL – Annane, Djillali et al. ‘Effects of Fluid Resuscitation With Colloids vs Crystalloids on Mortality in Critically Ill Patients Presenting With Hypovolemic Shock: The CRISTAL …
Imaging and echocardiography key papers
Echocardiography Ultrasound CT
Metabolic and endocrine key papers
Glucose control CGAO-REA – Kalfon P et al. ‘Tight Computerized versus Conventional Glucose Control in the ICU: A Randomized Controlled Trial’. Intensive Care Medicine 40, no. 2 (February 2014): 171–181. doi:10.1007/s00134-013-3189-0. Van den Berghe G. ‘Intensive Insulin Therapy in Critically Ill Patients’. The New England Journal of Medicine 345, no. 19 (8 November 2001): …
Neurology and sedation key papers
Out-of-hospital arrest management – see here
Obstetrics key papers
Overviews and perspective ICNARC Female admissions (aged 16-50 years) to adult, general critical care units in England, Wales and Northern Ireland, reported as “currently pregnant” or “recently pregnant” ICNARC report 2009 Φ Neligan PH, and Laffey JG. ‘Clinical Review: Special Populations–Critical Illness and Pregnancy’. Critical Care (London, England) 15, no. 4 (2011): 227. doi:10.1186/cc10256.Φ Plaat …
Resp table
ARDS Ventilation Strategy Eichacker P et al. Meta-analysis of acute lung injury and acute respiratory distress syndrome trials testing low tidal volumes. American Journal of Respiratory and Critical Care Medicine 2002 166: 1510-4 Needham D et al. ‘Lung Protective Mechanical Ventilation and Two Year Survival in Patients with Acute Lung Injury: Prospective Cohort …
Respiratory and airway key papers
Ventilation Strategy Amato MBP et al.
Trauma and burns key papers
Trauma Bickell WH et al. ‘Immediate versus Delayed Fluid Resuscitation for Hypotensive Patients with Penetrating Torso Injuries’. The New England Journal of Medicine 331, no. 17 (27 October 1994): 1105–1109. doi:10.1056/NEJM199410273311701. CRASH – Roberts I et al.‘ Effect of Intravenous Corticosteroids on Death within 14 Days in 10008 Adults with Clinically Significant Head Injury (MRC CRASH Trial): …