Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial | Dec 2024 | JAMA | Arleth | BottomLine |
Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage SAHARA | Dec 2024 | NEJM | English | Bottomline |
Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury: The TRAIN Randomized Clinical Trial | Nov 2024 | JAMA | Taccone | BottomLine |
Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium: Randomized Controlled Trial | Oct 2024 | Neurocrit Care | Zakhary | BottomLine |
Validating quantitative pupillometry thresholds for neuroprognostication after out‑of‑hospital cardiac arrest. A predefined substudy of the Blood Pressure and Oxygenations Targets After Cardiac Arrest (BOX)‑trial | Sep 2024 | ICM | Nyholm | BottomLine |
Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients with Sepsis The BLING III Randomized Clinical Trial | Aug 2024 | JAMA | Dulhunty | BottomLine |
Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation (REVISE) | Jul 2024 | NEJM | Cook | BottomLine |
Ultra-Early and Short-Term Tranexamic Acid Treatment in Patients With Good- and Poor-Grade Aneurysmal Subarachnoid Hemorrhage. ULTRA | 2024 Jun 25 | Neurology | Tjerkstra | |
Noninvasive Ventilation for Preoxygenation during Emergency Intubation PREOXI | Jun 2024 | NEJM | Gibbs | BottomLine |
Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury HEMOTION | Jun 2024 | NEJM | Turgeon | BottomLine |
Decompressive craniectomy plus best medical treatment versus best medical treatment alone for spontaneous severe deep supratentorial intracerebral haemorrhage: a randomised controlled clinical trial. SWITCH | 2024 Jun 1 | Lancet | Beck | |
Trial of Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH) | Apr 2024 | NEJM | Pradilla | BottomLine |
Microaxial Flow Pump or Standard Care in Infarct-Related Cardiogenic Shock (DanGer Shock) | Apr 2024 | NEJM | Moller | |
Empagliflozin after Acute Myocardial Infarction (EMPACT-MI) | Apr 2024 | NEJM | Butler | |
Antibiotics With or Without Rifaximin for Acute Hepatic Encephalopathy in Critically Ill Patients With Cirrhosis: A Double-Blind, Randomized Controlled (ARiE) Trial | Jan 2024 | Am J Gastro | Kulkarni | Bottom Line |