2022 Articles

Extracorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock: Results of the ECMO-CS Randomized Clinical Trial.2022 Nov 6CirculationOstadal P
Duration of Device-Based Fever Prevention after Cardiac Arrest. BOX2022 Nov 6N Engl J MedHassager C
Early Active Mobilization during Mechanical Ventilation in the ICU. TEAM2022 Nov 10N Engl J MedANZICS Clinical Trials Group.
Effect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge Among Patients Resuscitated After Out-of-Hospital Cardiac Arrest: The EXACT Randomized Clinical Trial.2022 Nov 8JAMA
Bernard SA
Spontaneous-Breathing Trials with Pressure-Support Ventilation or a T-Piece. TIPEX2022 Nov 17N Engl J MedThille AW
Defibrillation Strategies for Refractory Ventricular Fibrillation. DOSEVF2022 Nov 6N Engl J MedCheskes SBottom Line
Effect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial. SuDDICU2022 Nov 15JAMASuDDICU InvestigatorsBottom line
Operative vs Nonoperative Treatment of Acute Unstable Chest Wall Injuries: A Randomized Clinical Trial. TBL Mini2022 Nov 1JAMA SurgDehghan NBottom Line
Oxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation. PILOT2022 Nov 10N Engl J MedSemler MW
Haloperidol for the Treatment of Delirium in ICU Patients. AID ICU2022 Oct 26N Engl J MedAndersen-Ranberg NC
Management of Cerebral VasoSpasm after Aneurysmal Subarachnoid Hemorrhage (IMCVS)-A Phase 2 Randomized Controlled Trial.2022 Oct 20J Clin MedVatter H

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest. BOX BP		2022 Oct 20N Engl J MedKjaergaard JBottom Line
Temperature Control After In-Hospital Cardiac Arrest: A Randomized Clinical Trial2022 Sep 28CircWolfrum
Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis2022 Sep 15N Engl J MedDe MadariaBottom Line
Effect of Fluid Bolus Administration on Cardiovascular Collapse Among Critically Ill Patients Undergoing Tracheal Intubation: A Randomized Clinical Trial (PREPARE II)2022 JulyJAMARussellBottom Line
(1 → 3)-β-D-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial2022 JulICMBloosBottom Line
Restriction of Intravenous Fluid in ICU Patients with Septic Shock (CLASSIC)2022 Jun 30N Engl J MedMeyhoffBottom Line
Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit2022 Jun 15N Engl J MedLamontagneBottom Line
Tranexamic Acid in Patients Undergoing Noncardiac Surgery.2022 May 26N Engl J MedDevereaux PJ
Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Trial.2022 May 17JAMABoselBottom Line
Randomized Clinical Study of Temporary Transvenous Phrenic Nerve Stimulation in Difficult-to-Wean Patients.2022 May 15Am J Respir Crit Care MedDres M
Effect of Early vs Late Supplemental Parenteral Nutrition in Patients Undergoing Abdominal Surgery: A Randomized Clinical Trial2022 May 1JAMAGauBottom Line
Prophylactic melatonin for delirium in intensive care (Pro-MEDIC): a randomized controlled trial2022 AprICMWibrowBottom Line
Diuretics Versus Volume Expansion in the Initial Management of Acute Intermediate High-Risk Pulmonary Embolism2022 AprLungFerrariBottom Line
Endovascular Therapy for Acute Stroke with a Large Ischemic Region.2022 Apr 7N Engl J Med
Yoshimura S		Bottom Line
Treating Rhythmic and Periodic EEG Patterns in Comatose Survivors of Cardiac Arrest. TELSTAR2022 Feb 24N Engl J MedRuijter BJBottom Line
Effect of Intra-arrest Transport Extracorporeal Cardiopulmonary Resuscitation and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial.2022 Feb 22JAMABelohlavek JBottom Line
Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial.2022 Feb 8JAMAPerkins GD
A three-step support strategy for relatives of patients dying in the intensive care unit: a cluster randomised trial.2022 Feb 12LancetKentish-Barnes NBottom Line
Effect of Moderate Hypothermia vs Normothermia on 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial Extracorporeal Membrane Oxygenation (HYPO-ECMO)2022 Feb 1JAMALevyBottom Line
Fentanyl versus placebo with ketamine and rocuronium for patients undergoing rapid sequence intubation in the emergency department: The FAKT study-A randomized clinical trial.2022 Jan 22Acad Emerg MedFerguson IBottom Line
A three-step support strategy for relatives of patients dying in the intensive care unit: a cluster randomised trial2022 Jan 19LancetKentish-Barnes
Etomidate versus ketamine for emergency endotracheal intubation: a randomized clinical trial. EvK2022
Jan		Intensive Care MedMatchett