A recent Cochrane review suggests probiotics (unspecified) reduce the incidence of C.diff diarrhoea (or symptomatic infection), but not C.diff infection per se. High heterogeneity, low quality of evidence, some counter-intuitive findings but somehow a moderate level recommendation that probiotics are good for patients on antibiotics. NB this was not an analysis of critically ill patients!
Probiotics to prevent C.diff diarrhoea: flawed evidence but Cochrane folk recommend it!
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June 1, 2014
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