Must Reads :
Guidance for Delirium in the Critically Ill Patient (ICS Feb 25)
Beginners Guide to Green Teams in the ICU (ICS)
Martha’s Rule (ICS statement)
Quick Reference Handbook for Obstetric Emergencies (OAA)
Patient safety: SALG updates, NPSA alerts, Preventing Future Deaths
Others:
Recent Trials
Recent Guidelines and Consensus Statements
Article/Guideline Search
Social Media
(Approximately 500 articles picked by ICMWK as practice-informing)
Recent ICM Trials (fuller table here)
| Title | Date | Abstract | Author | Comment |
|---|---|---|---|---|
| Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial | Dec 2024 | JAMA | Arleth | BottomLine |
| Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage SAHARA | Dec 2024 | NEJM | English | Bottomline |
| Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury: The TRAIN Randomized Clinical Trial | Nov 2024 | JAMA | Taccone | BottomLine |
| Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium: Randomized Controlled Trial | Oct 2024 | Neurocrit Care | Zakhary | BottomLine |
| Validating quantitative pupillometry thresholds for neuroprognostication after out‑of‑hospital cardiac arrest. A predefined substudy of the Blood Pressure and Oxygenations Targets After Cardiac Arrest (BOX)‑trial | Sep 2024 | ICM | Nyholm | BottomLine |
| Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients with Sepsis The BLING III Randomized Clinical Trial | Aug 2024 | JAMA | Dulhunty | BottomLine |
| Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation (REVISE) | Jul 2024 | NEJM | Cook | BottomLine |
| Ultra-Early and Short-Term Tranexamic Acid Treatment in Patients With Good- and Poor-Grade Aneurysmal Subarachnoid Hemorrhage. ULTRA | 2024 Jun 25 | Neurology | Tjerkstra | |
| Noninvasive Ventilation for Preoxygenation during Emergency Intubation PREOXI | Jun 2024 | NEJM | Gibbs | BottomLine |
| Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury HEMOTION | Jun 2024 | NEJM | Turgeon | BottomLine |
| Decompressive craniectomy plus best medical treatment versus best medical treatment alone for spontaneous severe deep supratentorial intracerebral haemorrhage: a randomised controlled clinical trial. SWITCH | 2024 Jun 1 | Lancet | Beck | |
| Trial of Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH) | Apr 2024 | NEJM | Pradilla | BottomLine |
| Microaxial Flow Pump or Standard Care in Infarct-Related Cardiogenic Shock (DanGer Shock) | Apr 2024 | NEJM | Moller | |
| Empagliflozin after Acute Myocardial Infarction (EMPACT-MI) | Apr 2024 | NEJM | Butler | |
| Antibiotics With or Without Rifaximin for Acute Hepatic Encephalopathy in Critically Ill Patients With Cirrhosis: A Double-Blind, Randomized Controlled (ARiE) Trial | Jan 2024 | Am J Gastro | Kulkarni | Bottom Line |
| Landiolol and Organ Failure in Patients With Septic Shock: The STRESS-L Randomized Clinical Trial | 2023 Nov | JAMA | Whitehouse | Bottom Line |
| Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia | 2023 Oct | NEJM | Ehrman | |
| Ceftobiprole for Treatment of Complicated Staphylococcus aureus Bacteremia | 2023 Oct | NEJM | Holland | |
| Timing of Complete Revascularization with Multivessel PCI for Myocardial Infarction | 2023 Oct | NEJM | Stahli | |
| Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest | 2023 Oct | Lancet | Patterson | Bottom Line |
| Early and Empirical High-Dose Cryoprecipitate for Hemorrhage After Traumatic Injury | 2023 Oct | JAMA | Davenport | Bottom Line |
| Continuous vs Intermittent Meropenem Administration in Critically Ill Patients With Sepsis: The MERCY | 2023 June | JAMA | Monti G | |
| Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults | 2023 June | NEJM | Prekker ME | Bottom Line |
| Mild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest | 2023 June | NEJM | Eastwood G | Bottom Line |
| Prehospital Tranexamic Acid for Severe Trauma | 2023 June | NEJM | Gruen RL | Bottom Line |
| Platelet Transfusion before CVC Placement in Patients with Thrombocytopenia | 2023 May | NEJM | van Barle F | Bottom Line |
| Decompressive Craniectomy versus Craniotomy for Acute Subdural Hematoma | 2023 April | NEJM | Hutchinson P | |
| Hydrocortisone in Severe Community-Acquired Pneumonia | 2023 Mar | NEJM | Dequin PF | Bottom Line |
| Extracorporeal Carbon Dioxide Removal to Avoid Invasive Ventilation During Exacerbations of Chronic Obstructive Pulmonary Disease: VENT-AVOID Trial – A Randomized Clinical Trial | 2024 Mar | Am J Resp CCM | Duggal | |
| Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension – CLOVERS | 2023 Feb | NEJM | Shapiro N | Bottom Line |
| Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest | 2023 Jan | NEJM | Suverein M | Bottom Line |
Recent guidelines & consensus statements (table)
| Perioperative fluid management: evidence-based consensus recommendations from the international multidisciplinary PeriOperative Quality Initiative. | Dec 2024 | Br J Anaesth | Ostermann | |
| Peri-operative pain management in adults: a multidisciplinary consensus statement from the Association of Anaesthetists and the British Pain Society. | 2024 Nov | Anaesthesia | AA and BPS | |
| 2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). | Oct 2024 | Eur Heart J | ESC | |
| Reversal of direct oral anticoagulants: guidance from the SSC of the ISTH | Oct 2024 | J Thromb Haemost | ISTH | |
| Perioperative fluid management: evidence-based consensus recommendations from the international multidisciplinary PeriOperative Quality Initiative | Sep 2024 | BJA | Ostermann | |
| Management of patients with an electrical storm or clustered ventricular arrhythmias: a clinical consensus statement of the European Heart Rhythm Association of the ESC | Mar 2024 | Europace | ESC et al | |
| European Academy of Neurology/Peripheral Nerve Society Guideline on diagnosis and treatment of Guillain–Barré syndrome | Oct 2023 | J Periph Nerve S | Eur Acad Neur | |
| ESPEN practical and partially revised guideline: Clinical nutrition in the intensive care unit | Sep 2023 | Clin Nutr | ESPEN | |
| EASL Clinical Practice Guidelines on acute-on-chronic liver failure | Aug 2023 | J Hepatol | EASL | |
| European society of Clinical Microbiology and Infectious Diseases guidelines on diagnosis and treatment of brain abscess in children and adults | Aug 2023 | Clin Microb Inf | ESCMID | |
| A New Global Definition of Acute Respiratory Distress Syndrome | Jul 2023 | Am J Resp Crit Care | Matthay | |
| Lung ultrasound in acute and chronic heart failure: a clinical consensus statement of the European Association of Cardiovascular Imaging | Jul 2023 | Eur Heart J C Im | EACVI | |
| ESICM guidelines on acute respiratory distress syndrome | June 2023 | ICM | ESICM | |
| Consensus Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery | June 2023 | World J Surg | ERAS soc | |
| Targeted temperature management in patients with intracerebral haemorrhage, subarachnoid haemorrhage, or acute ischaemic stroke | May 2023 | BJA | NTCR group | |
| Use of albumin infusion for cirrhosis-related complications: An international position statement | May 2023 | J Hepatol | Bai (LCC ISIG) | |
| Quality indicators for post-resuscitation care after out-of-hospital cardiac arrest: a joint statement | April 2023 | Eur Heart J Card | AACA, ESC, ESICM | |
| ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia | April 2023 | Eur Resp J | Martin-Loeches | |
| Society of Anesthesia and Sleep Medicine Position Paper on Patient Sleep During Hospitalization | April 2023 | An and Analg | SASM | |
| Symptom Assessment for Mechanically Ventilated Patients: Principles and Priorities | April 2023 | AATS | ATS workshop | |
| The new timing in acute care surgery (new TACS) classification | April 2023 | World J Em Surg | WSES | |
| Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU | May 2023 | CCM | SCCM | |
| CT Angiography for diagnosing death using DNC Consensus Guideline | 2023 Jan | FICM/ICS | FICM/ICS | |
| Implementing human factors in anaesthesia: guidance for clinicians, departments and hospitals | 2023 Jan | Anaesthesia | Kelly | |
| Early management of isolated severe traumatic brain injury patients in a hospital without neurosurgical capabilities: a consensus and clinical recommendations of the World Society of Emergency Surgery (WSES) | 2023 Jan | BMC | Picetti | |
| Midnight Law: Relatives Recording Phone Conversations | 2019 Oct | FICM |
