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Be balanced when resuscitating sepsis?

Balanced fluids RadhunathanRaghunathan has used some interesting statistics to try and extract the effects of using Saline or Ringer’s lactate in resuscitating sepsis. Elixhauser comborbidities, 5:1 greedy matching, Generalized Estimating Equation models, and “missing-ness” are just a few of the terms I didn’t understand.

Nevertheless this appears to be a retrospective study that suggests there’s measurable mortality benefit in using balanced resuscitation fluid in the septic adult. The greater the proportion of balanced fluid the better they did.

Hypothesis generated!

1 comment

  1. andrew gerety

    metabolic theory of septic shock
    http://www.wjgnet.com/2220-3141/full/v3/i2/45.htm

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