Talk of the town

Current ICMWK postDear SIRS

Sepsis 3: Rise of the SOFA. The new consensus on definitions relating to sepsis. A different slant but any better?


Recent ICM trials/studies 

1. Long term quality of life in severe sepsis survivors, assessed by analysis of PROWESS-SHOCK and ACCESS trials.

2. SFELLOW Investigators and the Pragmatic Critical Care Research Group. Randomized Trial of
Apneic Oxygenation during Endotracheal Intubation of the Critically Ill. Am Respir Crit Care Med. 2016 Feb 1;193(3):273-80.

3. Outcome of Patients with Interstitial Lung Disease Treated with Extracorporeal Membrane Oxygenation
for Acute Respiratory Failure. Am J Respir Crit Care Med. 2016 Mar 1;193(5):527-33

4. Normocaloric versus hypocaloric feeding on the outcomes of ICU patients: a systematic review and meta-analysis. Intensive Care Med. 2016 Mar;42(3):316-23. 

5. Effect of Postextubation High-Flow Nasal Cannula vs Conventional Oxygen Therapy on Reintubation in Low-Risk Patients: A Randomized Clinical Trial. JAMA. 2016 Mar 15. 

6. Effect of Noninvasive Ventilation on Tracheal Reintubation Among Patients With Hypoxemic Respiratory Failure Following Abdominal Surgery: A Randomized Clinical Trial. JAMA. 2016 Mar 15.

7. DahLIA Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial. JAMA. 2016 Mar 15.

8. van Vught LA et al. MARS Consortium. Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in
the Intensive Care Unit After Admission for Sepsis. JAMA. 2016 Mar 15.

Recent FOAMcc selection

 Other recent ICMWK posts

Recent guidelines

SOFA flying

Sepsis 3: rise of the SOFA

Sepsis remains a syndrome without a validated criterion or standard diagnostic test but increasingly comprehensive data sets are making it easier to test validity of  potential criteria. The current instalment of this work in progress has refined the definition of sepsis in light of recent analyses and opinion. Sepsis is life-threatening organ dysfunction caused by a dysregulated …

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bw blood

Fighting ‘traditional nihilism’ re haematological malignancy in ICU

A guidance group and a sounding board of 50 UK experts has published guidelines on the management and ICU admission of critically ill adult patients with haematological malignancies. Part of the driving force for this was the ‘traditional nihilism’ in the critical care community about these patients, meaning disagreements regarding the benefit of admission to ICU are not …

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