Talk of the town

Current ICMWK post

A briefer summary of the management of severe traumatic brain injury – from the new BTF guidelines.


Recent ICM trials/studies 

  1. Gershengorn HB, et al. Association of Intensive Care Unit Patient-to-Intensivist Ratios With Hospital Mortality. JAMA Intern Med. 2017 Mar 1;177(3):388–96.
  2. Serpa Neto A, et al. Associations between ventilator settings during extracorporeal membrane oxygenation for refractory hypoxemia and outcome in patients with acute respiratory distress syndrome: a pooled individual patient data analysis : Mechanical ventilation during ECMO. Intensive Care Med. 2016 Nov;42(11):1672–84.
  3. Cortegiani A et al. Associations of Antifungal Treatments With Prevention of Fungal Infection in Critically Ill Patients Without Neutropenia. JAMA. 2017 17;317(3):311–2.
  4. Keh D et al. Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis: The HYPRESS Randomized Clinical Trial. JAMA. 2016 Nov 1;316(17):1775–85.
  5. Legriel S et al. Hypothermia for Neuroprotection in Convulsive Status Epilepticus. N Engl J Med. 2016 22;375(25):2457–67.
  6. Scales DC et al. Improving Appropriate Neurologic Prognostication after Cardiac Arrest. A Stepped Wedge Cluster Randomized Controlled Trial. Am J Respir Crit Care Med. 2016 Nov 1;194(9):1083–91.
  7. IRONMAN Investigators, Litton E et al. Intravenous iron or placebo for anaemia in intensive care: the IRONMAN multicentre randomized blinded trial : A randomized trial of IV iron in critical illness. Intensive Care Med. 2016 Nov;42(11):1715–22.
  8. Rygård SL et al. Long-term outcomes in patients with septic shock transfused at a lower versus a higher haemoglobin threshold: the TRISS randomised, multicentre clinical trial. Intensive Care Med. 2016 Nov;42(11):1685–94.
  9. Arabi YM et al. Permissive Underfeeding or Standard Enteral Feeding in High- and Low-Nutritional-Risk Critically Ill Adults. Post Hoc Analysis of the PermiT Trial. Am J Respir Crit Care Med. 2017 Mar 1;195(5):652–62.

Recent FOAMcc selection

Recent guidelines

 Other recent ICMWK posts

Updated 14/3/17

Severe traumatic brain injury reguidelined

Guidelines for the management of severe traumatic brain injury Brain trauma foundation: 4th edition, 2016   This is a brief summary and some of the wording is changed for brevity, hopefully without too much loss of accuracy. Although not explicitly stated on the guidelines, ‘Severe brain injury’ is generally defined as a brain injury resulting …

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Sepsis 3: rise of the SOFA

Sepsis remains a syndrome without a validated criterion or standard diagnostic test but increasingly comprehensive data sets are making it easier to test validity of  potential criteria. The current instalment of this work in progress has refined the definition of sepsis in light of recent analyses and opinion. Sepsis is life-threatening organ dysfunction caused by a dysregulated …

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