High flow humidified nasal oxygen for respiratory failure has been gaining popularity both in adult and paediatric care in recent years. A number of studies have shown promising results. Announced last year but published this month, FLORALI was a multicenter, sealed randomization, pragmatic RCT with a well-defined study protocol, performed in more than 20 ICUs in France and …
Chavez confirms the great predictive value of ultrasound in detecting pneumonia. We know more than 80% of pneumonia patients have disease extending to the pleura so this is no real surprise. How well trained do you need to be though?
Cochranized in the past, macrolides (usually azithromycin) seem more convincingly beneficial regarding mortality and treatment failure in pneumonia (especially in the elderly). This large but retrospective VA registry analysis supports this suggestion. The finding of more MIs but fewer ‘cardiac events’ is confusing. First line for everyone, include it in the initial antimicrobials, continue it …
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