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Metabolic and endocrine key papers

Glucose control

CGAO-REA – Kalfon P et al.
‘Tight Computerized versus Conventional Glucose Control in the ICU: A Randomized Controlled Trial’.
Intensive Care Medicine 40, no. 2 (February 2014): 171–181. doi:10.1007/s00134-013-3189-0.
Van den Berghe G.
‘Intensive Insulin Therapy in Critically Ill Patients’.
The New England Journal of Medicine 345, no. 19 (8 November 2001): 1359–1367. doi:10.1056/NEJMoa011300.
Van den Berghe G.
‘Intensive Insulin Therapy in the Medical ICU’.
New England Journal of Medicine 354, no. 5 (2006): 449. 
COIITSS – Annane D et al.
‘Corticosteroid Treatment and Intensive Insulin Therapy for Septic Shock in Adults: A Randomized Controlled Trial’.
JAMA: The Journal of the American Medical Association 303, no. 4 (27 January 2010): 341–348. doi:10.1001/jama.2010.2. 
NICE-SUGAR – Griesdale DEG et al. (BL review)
‘Intensive Insulin Therapy and Mortality among Critically Ill Patients: A Meta-Analysis Including NICE-SUGAR Study Data’.
Canadian Medical Association Journal 180, no. 8 (24 March 2009): 821–827. doi:10.1503/cmaj.090206.
DIGAMI – Malmberg, K.
‘Prospective Randomised Study of Intensive Insulin Treatment on Long Term Survival after Acute Myocardial Infarction in Patients with Diabetes Mellitus. DIGAMI (Diabetes Mellitus, Insulin Glucose Infusion in Acute Myocardial Infarction) Study Group’.
BMJ (Clinical Research Ed.) 314, no. 7093 (24 May 1997): 1512–1515. 
VISEP – Brunkhorst FM et al.
‘Intensive Insulin Therapy and Pentastarch Resuscitation in Severe Sepsis’.
The New England Journal of Medicine 358, no. 2 (10 January 2008): 125–139. doi:10.1056/NEJMoa070716.

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