Surely statins are useful for something on the ICU?

StatinVAPRecent articles on statins for ARDS treatment, VAP treatment and COPD excerbation prevention have all been disappointing. In the lab they are anti-inflammatory, protect coagulation pathways, and inhibit micro-organisms. On the unit there have been suggestions that they prevent the onset of, and reduce mortality in, severe infections and sepsis, but this has been difficult to replicate in larger studies or analyses.

Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong>