Stress hyperglycaemia and lactataemia

Lactate glucoseAustralian lactate enthusiasts have taken a huge dataset and discovered high sugar is not an independent risk factor when the lactate is also high. Given they both take part in the Cori cycle and glycolysis maybe this shouldn’t be a surprise but maybe it also explains NICE-SUGAR and should reassure us that semi-tight control is right. Increasingly clear we still don’t really know how to interpret lactate levels?