«

»

Probiotics to prevent C.diff diarrhoea: flawed evidence but Cochrane folk recommend it!

c diff forrestA recent Cochrane review suggests probiotics (unspecified) reduce the incidence of C.diff diarrhoea (or symptomatic infection), but not C.diff infection per se. High heterogeneity, low quality of evidence, some counter-intuitive findings but somehow a moderate level recommendation that probiotics are good for patients on antibiotics. NB this was not an analysis of critically ill patients!