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3 sepsis papers at once

sepsis hand

1. First of the 3 attempts to confirm goal-directed therapy benefit, PROCESS, has arrived and shows no benefit of a protocolised approach ‘v’ usual care. Look carefully at the details, particularly at the protocol changes.

2. MAP targeting in septic shock. 65-70 or 80-85 mmHg? No mortality difference in 776 patients but less kidney injury in the higher group,in SEPSISPAM.

3. Albumin as part of fluid resuscitation in sepsis and septic shock patients lead to no outcome difference in ALBIOS. But maybe save it just for septic shock.

 

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