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Lethal underdose – antimicrobials in ICU

MIC graphKnow about fT>MIC? It’s becoming increasingly obvious that our antibiotic dosing in ICU is suboptimal in a considerable number of critically ill patients – 16% in this study.

Should we be giving these drugs differently? Continuous infusion or extended intermittent infusions are probably the way forward for many cases. Bling II should help to clear this up.